Can Homemade Microdosing Capsules Spoil?

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If you’re going to microdose, you can use homemade microdosing capsules, but of course it’s nice if they don’t spoil. It is important to prepare and store your capsules properly. In this blog, you’ll learn how to make sure your microdosing capsules last as long as possible.

All about homemade microdosing capsules

Microdosing is a way to support your health. You take a very low dose of a mind-altering drug (such as magic mushrooms or truffles), which can have a positive effect on your physical and mental well-being. Why make your own capsules?

You can grow your own mushrooms, dry your harvest and make microdoses with them. This can also be done with truffles. Ready-made packs microdose truffles purchase is also an option. These are fresh truffles, and once opened do not have a long shelf life. The dosages may still be a bit too high for you (they are 1 gram), so it may be a good idea to dry them, weigh them and put them in a capsule.

There is a lot on the internet about the drying mushrooms and truffles. For example, use the information on Eworid.org about drying magic mushrooms. You don’t need any special equipment for this. Then you can buy regular or vegetarian capsules to hold your dried microdoses. These are available in different sizes. You can take the smallest capsule because only a microdose goes into it.

How long do homemade microdosing capsules last?

If you store your homemade microdosing capsules properly, they certainly won’t spoil easily. They should last for at least a year without sacrificing quality and effectiveness. If you don’t store them properly, they can spoil: they lose their strength or can go moldy, and this can happen within a few months.

What affects shelf life:

  • Light
  • Air
  • Moisture
  • Temperature

If your capsules are exposed to one or more of these factors, it could affect their shelf life. Not only do you risk mold, but also the breakdown of active ingredients, causing them to lose their efficacy. Proper storage of your homemade microdosing capsules is therefore essential.

capsules microdosing

How do I store my capsules?

Please note the following points when storing your capsules:

  • Avoid exposure to light: Sunlight is the enemy of psilocybin, the active ingredient in magic mushrooms and truffles. Direct sunlight causes the substances to break down, causing your capsules to lose efficacy. Therefore, store your homemade microdosing capsules in a dark place so they are less likely to spoil. Consider a locked kitchen cabinet or drawer. A dark glass jar is also great for storing them.
  • Cool and dry storage: Keep your capsules at a stable temperature, between 15 and 20 degrees. Keep them away from heat sources, such as an oven or heater. High temperatures can also be harmful to psilocybin.
  • Airtight and protected from moisture: It is also important to store your microdoses in airtight containers, where they also cannot be affected by moisture. Therefore, use airtight sealable glass jars or containers that can be sealed tightly.

By following these steps, you can ensure that your microdosing capsules have a long shelf life, at least a year.

How can you tell when your homemade microdosing capsules are spoiling?

Of course, it is very important to be able to recognize the signs of spoilage in your microdosing capsules. Here’s what you can look out for.

Change of color

You can tell from the capsules themselves that they are no longer good. They often darken and lose their original color or brightness. They are then no longer safe to use.

Fungi or bacteria

If you see visible contamination with mold or bacteria, then your capsules are definitely spoiled and no longer safe to take. Mold looks like dark spots on the capsules or if they are translucent you can see discoloration and fluffy growth on the contents. Dispose of these capsules immediately and do not use them, as they may pose health risks. For more information, see Molds on Food: Are they dangerous? from the USDA. Fungi can cause allergic reactions and be toxic.

Fragrance

Are your homemade microdosing capsules still safe or will they spoil? To find out, you can also sniff it. If you smell a musty, unpleasant odor, they are no longer good. Your capsules should smell neutral or at most have a somewhat earthy scent. If not, it’s better to get rid of them.

So to determine if your homemade capsules are still good, you can use your own senses. Look and smell carefully before taking a capsule and watch for abnormalities. If you doubt they are still good, take the safe bet. With spoiled products, it’s best not to take any chances.

microdosing mushrooms

Can you freeze capsules?

In principle, dried mushrooms and truffles can be frozen. That way they have a very long shelf life. This is an option if you grow your own mushrooms and can harvest larger quantities. But capsules are not suitable for freezing because they can be damaged. The capsule will expand and contract again under the influence of low temperatures, which can cause them to break or crack. This allows moisture to enter the capsules, which can affect the psilocybin.

Just make sure you store your capsules properly, as described above. They can then stay good for at least a year, which in most cases is long enough to make up your stock.

Scientific Insights on the Shelf Life of Psilocybin

  1. Influence of Storage Conditions on Psilocybin

    Research has shown that psilocybin remains most stable when dried mushrooms are stored in the dark at room temperature. Under these conditions, the concentration of psilocybin remains virtually unchanged for a period of 15 months. In contrast, storage in light leads to a significant decrease in psilocybin, with a 12% decrease after only one week. Storage at -80°C even resulted in a loss of nearly 90% of tryptamines, including psilocybin.

  2. Stability in Microdosing Capsules

    Although specific studies on the stability of psilocybin in microdosing capsules are limited, general guidelines suggest that if stored properly, these capsules can have a shelf life of one to two years or longer. Important factors for maintaining potency are avoiding light, air and moisture .

  3. Chemical Stability of Psilocybin

    Psilocybin is susceptible to degradation under the influence of light, oxygen and moisture. These factors can lead to a decrease in the psychoactive properties of the drug. Therefore, it is essential to store psilocybin-containing products under optimal conditions to maintain effectiveness.

Below is an overview of relevant scientific sources that substantiate the shelf life and stability of psilocybin in homemade microdosing capsules. These studies emphasize the importance of proper storage conditions to maintain the potency and safety of psilocybin products.

Scientific Sources on the Stability of Psilocybin

  1. Gotvaldová et al. (2021) -. Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis
    This study investigated the stability of psilocybin and related tryptamines in different parts of the mushroom Psilocybe cubensis. The results showed that storage in the dark at room temperature minimizes psilocybin degradation, while storage at -80°C leads to a significant decrease in tryptamines.
  2. Miraculix Lab (2025) – Do magic mushrooms go bad?
    A recent blog post discussing the chemical instability of psilocybin and psilocin. The author emphasizes that factors such as oxidation, enzymatic hydrolysis and photodegradation contribute to their degradation. It is recommended that dried mushrooms be stored in a dark, oxygen-free environment at controlled low temperatures to extend shelf life.
  3. Psychedelic.Support (2023) -. Storing Psilocybin: Best Practices for Magic Mushroom Storage
    This resource provides practical guidelines for storing psilocybin products. It emphasizes the importance of a cool, dark and dry storage environment, as well as the use of airtight containers to preserve the potency of psilocybin.

Links

  • Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis
    This study shows that psilocybin remains most stable when dried mushrooms are stored in the dark at room temperature. Storage at -80°C led to significant degradation of tryptamines.
    PubMed Link
  • Investigation into the temporal stability of aqueous standard solutions of psilocin and psilocybin using high performance liquid chromatography
    Studies on the stability of psilocybin and psilocin in aqueous solutions show that excluding light significantly extends stability. Both substances remained stable for seven days in the absence of light.
    PubMed Link

Using microdosing capsules

If you have stored your homemade capsules properly, you can enjoy them for a long time. It is wise, if you are going to microdose, to adopt a microdosing routine. In this, you do not take a dose daily to avoid habituation. For example, you can follow the Fadiman routine, taking a dose every two days.

If you are thinking about microdosing, seek the advice of your doctor first. Microdosing is not for everyone. If you use medication, see if microdosing will not affect your medication. If you decide it is something you do want to try, choose a reliable brand that offers high-quality products. Even if you take a very low dose of a mind-altering drug, it is always possible that you will suffer from side effects or unexpected effects, especially if you err on the side of dosage, as noted on Healthline.com. You may then experience paranoia, agitation, anxiety or increased heart rate.

Recommendations for Storage

  • Dark and Cool Environment: Store capsules in a dark place at a stable temperature between 15 and 20 degrees Celsius.
  • Airtight Packaging: Use airtight containers to minimize exposure to air and moisture.
  • Avoid Freezing: Freezing capsules is not recommended, as it can lead to condensation upon thawing, which can affect the psilocybin.

By following these storage guidelines, the shelf life and effectiveness of homemade microdosing capsules can be maximized.

Disclaimer

The information in this blog is for informational purposes only and does not replace medical advice. Always consult a doctor before starting microdosing or using homemade capsules. Shelf life and safety may vary depending on storage and ingredients. We are not responsible for any damages or health risks resulting from the use of this information. Check local laws about psychedelic substances before using them.

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